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$PRLD · Prelude Therapeutics Inc

Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients.

More about this company

Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing JAK2V617F, a driver mutation product for the treatment of myeloproliferative neoplasms, myelofibrosis (MF), polycythemia vera, and essential thrombocythemia (ET); KAT6A for the treatment of advanced breast cancer and other solid tumors; and mutated calreticulin degrader antibody conjugates to treat MF and ET. The company has collaboration with AbCellera Biologics to discover, develop, and commercialize novel degrader antibody conjugates. Prelude Therapeutics Incorporated was incorporated in 2016 and is based in Wilmington, Delaware.

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FiledFormActivist% of classConviction
2026-04-23SCHEDULE 13D/AORBIMED ADVISORS LLC16.0%Highfiling
2026-04-22SCHEDULE 13D/ABAKER BROS. ADVISORS LP15.5%Highfiling

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FiledInsiderRoleSharesValue
2026-04-23ORBIMED ADVISORS LLC (cluster of 2)director+10%-owner2,815,315$12,499,999Form 4
2026-04-23Bonita David P (cluster of 2)director+10%-owner2,815,315$12,499,999Form 4

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